Could a medication I’m taking make me feel depressed?

Several medications can produce depressive symptoms. Stay away from prescribed steroids like prednisone and the anabolic steroids used by bodybuilders. A few medications for heart problems like Serpasi (reserpine), antivirals like Foscavir (foscarnet), and oral acne medicines like Accutane (isotretinoin) can trigger or aggravate unipolar major depression. Ask your primary care doctor to make sure you do not get any medications that can cause or increase depression.