What physical symptoms are typical with serious depression?

During episodes of unipolar major depression, you are more likely to experience headaches, neckaches, backaches, shoulder pain, muscle pain, and joint pain. Stomachaches, nausea, cramping, and diarrhea occur more frequently in individuals suffering from unipolar major depression.

Pain problems probably result from the increased level of inflammation that occurs during the course of unipolar major depression [see Chapter 3, Diagnosis and Causes). Physical problems usually go away as your depression begins to lift after effective treatment.