A moderately strong nonnarcotic pain relief medication taken to relieve restless leg syndrome (RLS), supported by the results of an open-label trial, and other causes of nocturnal (nighttime) and chronic pain. Though tramadol (Ultram) is not a narcotic, it can cause dependence with long-term use. It usually does not cause constipation, however, unlike narcotic pain medications. Common side effects include drowsiness, euphoria, confusion, and disorientation. Tramadol also seems to have a mild antidepressant effect.